产品货号:
Z31068
中文名称:
ERBB3抗体
英文名称:
Anti-ERBB3 Antibody (Clone#OTI2F11)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ERBB3 Antibody (Clone#OTI2F11) |
指标别名 | c erbB 3;c erbB3;ErbB 3;ERBB3;erbB3 S;HER3;LCCS2;MDA BF 1;p180 ErbB3;p45 sErbB3;p85 sErbB3 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | ERBB3 |
克隆号 | OTI2F11 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human ERBB3 (NP_001973) produced in SF9 cell. |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases.This membrane-bound protein has a neuregulin binding domain but not an active kinase domain.It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation.However,it does form heterodimers with other EGF receptor family members which do have kinase activity.Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation.Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers,including prostate,bladder,and breast tumors.Alternate transcriptional splice variants encoding different isoforms have been characterized.One isoform lacks the intermembrane region and is secreted outside the cell.This form acts to modulate the activity of the membrane-bound form.Additional splice variants have also been reported,but they have not been thoroughly characterized.[provided by RefSeq,Jul 2008] |
Uniprot ID | P21860 |
推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索:ERBB3抗体,ERBB3单抗,Anti-ERBB3 Antibody (Clone#OTI2F11)