产品货号：
Z31054
中文名称：
ERAB/HSD17B10抗体
英文名称：
Anti-ERAB/HSD17B10 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ERAB/HSD17B10 Antibody |
| 指标别名 | 17 beta HSD 10;17b HSD10;ABAD;CAMR;DUPXp11.22;ERAB;HADH2;HCD2;HSD17B10;MHBD;MRPP2;MRX17;MRX31;MRXS10;SCHAD;SDR5C1;Type II HADH;XH98G2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | HSD17B10 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human ERAB Functions in mitochondrial tRNA maturation.Part of mitochondrial ribonuclease P,an enzyme composed of MRPP1/RG9MTD1,MRPP2/HSD17B10 and MRPP3/KIAA0391,which cleaves tRNA molecules in their 5'-ends.By interacting with intracellular amyloid-beta,it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). |
| 实际分子量 | 25KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ERAB is also known as HSD17B10 or HADH2.This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II,a member of the short-chain dehydrogenase/reductase superfamily.The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids,and is a subunit of mitochondrial ribonuclease P,which is involved in tRNA maturation.The protein has been implicated in the development of Alzheimer disease,and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency.Several alternatively spliced transcript variants have been identified,but the full-length nature of only two transcript variants has been determined. |
| Uniprot ID | Q99714 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Flow cytometry (FCM) 1:20 |
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