产品货号：
Z31011
中文名称：
Cyclin D1/CCND1抗体
英文名称：
Anti-Cyclin D1/CCND1 Antibody (Clone#OTI1G2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cyclin D1/CCND1 Antibody (Clone#OTI1G2) |
| 指标别名 | B cell lymphoma 1 protein;CCND1;cyclin D;Cyclin D1;D11S287E;G1/S specific cyclin D1;PRAD1;PRAD1 oncogene;U21B31 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | CCND1 |
| 克隆号 | OTI1G2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant protein of human CCND1 (NP_444284) produced in E.coli. |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Cyclin D1,also known as CCND1,is a human gene.The protein encoded by this gene belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle.Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle.Amplification or overexpression of cyclin D1 plays pivotal roles in the development of a subset of human cancers including parathyroid adenoma,breast cancer,colon cancer,lymphoma,melanoma,and prostate cancer.The cyclin D1 gene is overexpressed in human breast cancers and is required for oncogene-induced tumorigenesis.Brisken et al.(2003) found that prolactin induced IGF2 mRNA and IGF2 induced cyclin D1 protein expression in mouse mammary epithelial cultures.And they also concluded that IGF2 is a mediator of prolactin-induced alveologenesis and that prolactin,IGF2,and cyclin D1 are components of a developmental pathway in mammary gland. |
| Uniprot ID | P24385 |
| 基因名全称 | cyclin D1 |
| 蛋白名全称 | G1/S-specific cyclin-D1 |
| 推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索：Cyclin D1/CCND1抗体，Cyclin D1抗体，CCND1单抗，Anti-Cyclin D1/CCND1 Antibody (Clone#OTI1G2)