产品货号：
Z30782
中文名称：
ZBRK1/ZNF350抗体
英文名称：
Anti-ZBRK1/ZNF350 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZBRK1/ZNF350 Antibody |
| 指标别名 | ZFQR,ZBRK1,Zinc finger protein 350,KRAB zinc finger protein ZFQR |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | ZNF350 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ZBRK1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human ZBRK1.The immunogen is located within amino acids 410 - 460 of ZBRK1. |
| 计算分子量 | 60kDa |
| 成分 | ZBRK1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ZBRK1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors.ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1,a transcriptional regulator with tumor suppressor activity.ZBRK1 binds to a specific sequence within the GADD45 gene,supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription.Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD),and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements.These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions. |
| Uniprot ID | Q9GZX5 |
| 基因名全称 | Zinc finger protein 350 |
| 蛋白名全称 | Zinc finger protein 350 |
| 推荐稀释比 | ZBRK1 antibody can be used for detection of ZBRK1 by Western blot at 1μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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