产品货号：
Z30657
中文名称：
CBX4抗体
英文名称：
Anti-CBX4 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CBX4 Antibody |
| 指标别名 | CBX4;Chromobox protein homolog 4;E3 SUMO protein ligase CBX4;hPC2;NBP16;PC2;Polycomb 2 homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IF,WB |
| 基因名称 | CBX4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 90-115 of Human PC2 protein. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.Reactivity occurs against human PC2 protein. |
| 浓度 | 1.36mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | PC2 is the human homolog of the Drosophila 'Polycomb' (Pc) protein which has been identified as a gene family member associated with a cellular memory system that is responsible for the inheritance of gene activity by progeny cells.The human Pc homolog gene is more closely related to a Xenopus Pc homolog,XPc,than to a previously described human Pc homolog,CBX2 (hPc1).However,the hPc2 and CBX2/hPc1 proteins are shown to colocalize in interphase nuclei of human U-2 OS osteosarcoma cells,suggesting that the proteins are part of a common protein complex.The human protein is believed to function as a repressor of proto-oncogene activity and that interference with hPc2 function can lead to depression of proto-oncogene transcription and subsequently to cellular transformation.Other reports describe PC2 as a protein that has SUMO E3 activity for the corepressors CtBP and CtBP2. |
| Uniprot ID | O00257 |
| 推荐稀释比 | ELISA:1:10,000 - 1:40,000 IF Microscopy:1:100 - 1:400 IP:1:100 WB:1:1,000 - 1:4,000 |
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