产品货号:
Z30656
中文名称:
CBX4抗体
英文名称:
Anti-CBX4 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CBX4 Antibody |
指标别名 | CBX4;Chromobox protein homolog 4;E3 SUMO protein ligase CBX4;hPC2;NBP16;PC2;Polycomb 2 homolog |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IF |
基因名称 | CBX4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CBX4 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CBX4.The immunogen is located within amino acids 50 - 100 of CBX4. |
计算分子量 | 61kDa |
成分 | CBX4 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CBX4 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance.At least two distinct human PcG complexes have been identified.Polycomb repressive complex I (PRC1) contains CBX4/Pc2,HPH1 and RING domain-containing proteins (RING1,RING2 and BMI1).CBX4 (Chromobox protein homolog 4 or PC2),which functions as a transcriptional suppressor,is a candidate of KyoT2-binding proteins.It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation.Depletion of CBX4 results in decreased cellular resistance to ionizing radiation.CBX4 is directly involved in the cellular response to DNA damage. |
Uniprot ID | O00257 |
基因名全称 | Chromobox homolog 4 |
蛋白名全称 | Chromobox homolog 4 |
推荐稀释比 | CBX4 antibody can be used for detection of CBX4 by Western blot at 1μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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