产品货号:
Z30627
中文名称:
CCDC141抗体
英文名称:
Anti-CCDC141 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CCDC141 Antibody |
指标别名 | CAMDI,Coiled-coil domain-containing protein 141 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CCDC141 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CCDC141 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CCDC141.The immunogen is located within amino acids 40 - 90 of CCDC141. |
计算分子量 | 166kDa |
成分 | CCDC141 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CCDC141 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Coiled-coil domain-containing protein 141 (CCDC141),also known as CAMDI,is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II.CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner.Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes,suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development. |
Uniprot ID | Q6ZP82 |
基因名全称 | Coiled-coil domain containing 141 |
蛋白名全称 | Coiled-coil domain containing 141 |
推荐稀释比 | CCDC141 antibody can be used for detection of CCDC141 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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