产品货号：
Z30244
中文名称：
ZBTB48抗体
英文名称：
Anti-ZBTB48 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZBTB48 Antibody |
| 指标别名 | HKR3;pp9964;Protein HKR3;TZAP;ZBTB48;ZNF855 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | ZBTB48 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ZBTB48 recombinant protein (Position:Q24-E664). |
| 实际分子量 | 77KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Zinc finger and BTB domain containing 48 (ZBTB48),also known as telomeric zinc-finger associated protein (TZAP),is a protein that directly binds to the double-stranded repeat sequence of telomeres.In humans it is encoded by the ZBTB48 gene.ZBTB48,also named as TZAP and HKR3,is a 688 amino acid protein,which contains 1 BTB (POZ) domain and 11 C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family.ZBTB48 is detected in adrenal gland and neuroblastoma.ZBTB48 binds to and regulates the J and/or S elements in MHC II promoter.Zinc finger and BTB domain containing 48 (ZBTB48),also known as telomeric zinc-finger associated protein (TZAP),is a protein that triggers the trimming of telomeres in the absence of shelterin.ZBTB48,is a relatively uncharacterized POK family protein with a POZ-domain and 11 zinc finger domains.ZBTB48,is ubiquitously expressed in human tissues.The ZBTB48 gene is mapped to human chromosome 1p36,which is commonly rearranged (leiomyoma and leukemias) or deleted in various cancers (neuroblastoma,melanoma,Merkel cell carcinomas,pheochromocytoma and breast and colon carcinomas.A correlation between deletions or rearrangements of HKR3 and human cancer suggest a role for ZBTB48 as a potential tumor suppressor. |
| Uniprot ID | P10074 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | zinc finger and BTB domain containing 48 |
| 蛋白名全称 | Telomere zinc finger-associated protein |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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