产品货号：
Z30221
中文名称：
IGFBP5抗体
英文名称：
Anti-IGFBP5 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IGFBP5 Antibody |
| 指标别名 | IBP 5;IBP5;IGF binding protein 5;IGFBP 5;IGFBP5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | IGFBP5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human IBP5 protein. |
| 计算分子量 | 31KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | IBP5 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Insulin-like growth factor-binding protein 5 is a protein that in humans is encoded by the IGFBP5 gene.The expression of IGFBP5 by stable transfection and adenovirus-mediated infection is inhibitory to growth in 2 human breast cancer cell lines.IGFBP5 expression leads to G2/M cell cycle arrest and apoptosis.Stable expression of IGFBP5 in the breast cancer cell lines also inhibits the formation and growth of tumors following injection in athymic mice.It is concluded that IGFBP5 is a growth inhibitor and proapoptotic agent in breast cancer cells.Additionally,IGFBP-5 is expressed by fibroblasts,myoblasts and osteoblasts,making it the predominant IGFBP found in bone extracts.It has a strong affinity for hydroxyapatite,allowing it to bind to bone cells.When bound to extracellular matrix,IGFBP-5 is protected from proteolysis and potentiates IGF activity,but when it is soluble,IGFBP-5 is cleaved to a biologically inactive 21kDa fragment (1,2). |
| Uniprot ID | P24593 |
| 基因名全称 | Insulin-like growth factor-binding protein 5 |
| 蛋白名全称 | Insulin-like growth factor-binding protein 5 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
相关搜索：IGFBP5抗体，IGFBP5多抗，Anti-IGFBP5 Antibody