产品货号：
Z30220
中文名称：
IGFBP2抗体
英文名称：
Anti-IGFBP2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IGFBP2 Antibody |
| 指标别名 | BP2;IBP 2;IBP2;IGF binding protein 2;IGF BP53;IGFBP 2;IGFBP2 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | Igfbp2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived rat IGFBP2 recombinant protein (Position:E35-Q304). |
| 实际分子量 | 35KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP).All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues,which are clustered in the amino- and carboxy-terminal thirds of the molecule.IGFBPs modulate the biological activities of IGF proteins.Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins.Post-translational modifications of IGFBPs,including glycosylation,phosphorylation and proteolysis,have been shown to modify the affinities of the binding proteins to IGF.Human IGFBP-2 cDNA encodes a 328 amino acid (aa) residue precursor protein with a putative 39 aa residue signal peptide that is processed to generate the 289 aa residue mature protein.IGFBP-2 contains an integrin receptor recognition sequence (RGD sequence) but lacks potential N-linked glycosylation sites.During development,IGFBP-2 is expressed in a number of tissues.The highest expression level is found in the central nervous system.In adults,high expression levels are also detected in the central nervous system and in a number of reproductive tissues.IGFBP-2 binds preferentially to IGF II,exhibiting a 2-10 fold higher affinity for IGF II than for IGF I. |
| Uniprot ID | P12843 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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