产品货号：
Z30178
中文名称：
ZO-2/TJP2抗体
英文名称：
Anti-ZO-2/TJP2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZO-2/TJP2 Antibody |
| 指标别名 | Tight junction protein 2;Tight junction protein ZO 2;TJP2;X104;ZO 2;ZO2;ZO-2;Zona occludens protein 2;Zonula occludens protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | TJP2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of mouse TJP2(1149-1167aa AHSKRGYYSQPSRYRDTEL),identical to the related rat sequence. |
| 实际分子量 | 150KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TJP2(Tight Junction Protein 2),also known as Zona Occludens 2 or ZO2,is a protein that in humans is encoded by the TJP2 gene.Tight junction proteins(TJPs) belong to a family of membrane-associated guanylate kinase(MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions.Duclos et al.(1994) mapped the TJP2 gene telomeric to the Friedreich ataxia critical region on chromosome 9q13-q21.TJP2 lies about 70kb centromeric to the X123 gene and is transcribed in the centromere-to-telomere direction.Using in vitro assays and immunoprecipitation studies,Itoh et al.(1999) showed that the mouse Tjp1,Tjp2,and Tjp3 PDZ1 domains interacted with the C-terminal cytoplasmic domains of Cldn1 through Cldn8.In the mouse inner ear,Walsh et al.(2010) found that Tjp2 expression decreased rapidly between E16.5 and age 1 week to a level in adult mice that was approximately 50% of the level at birth(P0). |
| Uniprot ID | Q9Z0U1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | tight junction protein 2 |
| 蛋白名全称 | Tight junction protein ZO-2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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