Cleaved-COL4A3 (L1425)抗体

产品货号：

Z30147

中文名称：

Cleaved-COL4A3 (L1425)抗体

英文名称：

Anti-Cleaved-COL4A3 (L1425) Antibody

产品规格：

100μl

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-Cleaved-COL4A3 (L1425) Antibody
指标别名	COL4A3;Tumstatin;Goodpasture antigen;Collagen alpha-3(IV) chain
克隆性	Polyclonal
检验物种	human
应用范围	WB,ELISA
基因名称	COL4A3
抗体来源	Rabbit
抗体类型	IgG
免疫原	Synthesized peptide derived from human COL4A3
计算分子量	162KD
成分	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
纯化方式	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度	1mg/mL
产品形态	溶液
保存条件	-20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。
背景资料	Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene.Type IV collagen,the major structural component of basement membranes,is a multimeric protein composed of 3 alpha subunits.These subunits are encoded by 6 different genes,alpha 1 through alpha 6,each of which can form a triple helix structure with 2 other subunits to form type IV collagen.This gene encodes alpha 3.In the Goodpasture syndrome,autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli.The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein.A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis.This gene is also linked to an autosomal recessive form of Alport syndrome.The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region.Like the other members of the type IV collagen gene family,this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.
Uniprot ID	Q01955
基因名全称	Collagen alpha-3(IV) chain
蛋白名全称	Collagen alpha-3(IV) chain
推荐稀释比	WB 1:500～1:2000 ELISA 1:5000

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