产品货号：
Z30102
中文名称：
ZIP1/SLC39A1抗体
英文名称：
Anti-ZIP1/SLC39A1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZIP1/SLC39A1 Antibody |
| 指标别名 | ZIP1,ZIRTL,IRT1,ZIP1,CGI-08,CGI-71,Zinc transporter ZIP1,Solute carrier family 39 member 1,ZIP-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | SLC39A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ZIP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human ZIP1.The immunogen is located within amino acids 40 - 90 of ZIP1. |
| 计算分子量 | 34kDa |
| 成分 | ZIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ZIP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | ZIP1,also known as ZIRTL (zinc-iron regulated transporter-like),is the first mammalian member of a family of divalent ion transporters.Zinc is an essential ion for cells and plays significant roles in the growth,development,and differentiation.ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer.More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-百B,leading to down-regulation of the antiapoptotic protein Bcl-2,Bcl-XL,and the apoptosis inhibitor XIAP,reducing the malignant potential of prostate cancer cells in vitro and in vivo. |
| Uniprot ID | Q9NY26 |
| 基因名全称 | Solute carrier family 39 (zinc transporter),member 1 |
| 蛋白名全称 | Solute carrier family 39 (zinc transporter),member 1 |
| 推荐稀释比 | ZIP1 antibody can be used for detection of ZIP1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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