产品货号：
Z30072
中文名称：
CUL5抗体
英文名称：
Anti-CUL5 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CUL5 Antibody |
| 指标别名 | Cullin-5;CUL-5;Vasopressin-activated calcium-mobilizing receptor 1;VACM-1;CUL5;VACM1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,IP,WB |
| 基因名称 | CUL5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an N-Terminal region near amino acids 1-25 of Human Cul5 (N-terminus) coupled to KLH. |
| 计算分子量 | 91kDa |
| 成分 | 0.01% (w/v) Sodium Azide |
| 纯化方式 | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.This product reacts with human Cullin 5.Cross-reactivity is expected against mouse Cul5 based on a high degree of sequence homology.Cross-reactivity with other human cullins may occur. |
| 浓度 | 85mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination,as well as binding to various specificity factors to recruit substrates.Cullin 5 is a component of E3 ubiquitin ligase complexes,which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55kDa protein.Cullin 5 may form a cell surface vasopressin receptor.Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2),RBX1 and MUF1,complexes with elongin BC complex (TCEB1 and TCEB2),RXB1 and TCEB3 or SOCS1 or WSB1;elongin BC complex (TCEB1 and TCEB2),RBX1 and VHL;elongin BC complex (TCEB1 and TCEB2),RBX1,adenovirus type 5 E1B-55kDa protein and adenovirus type 5 E4-orf6.Cullin 5 Interacts with RBX1 and RNF7. |
| Uniprot ID | Q93034 |
| 基因名全称 | Cullin-5 |
| 推荐稀释比 | ELISA:1:2,000 - 1:10,000 IHC:User Optimized IP:User Optimized WB:1:500 - 1:1,000 |
相关搜索：CUL5抗体，CUL5多抗，Anti-CUL5 Antibody