产品货号:
Z29925
中文名称:
CARD11抗体
英文名称:
Anti-CARD11 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CARD11 Antibody |
指标别名 | BIMP3;CARD11;Carma 1;CARMA1 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CARD11 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CARMA1 antibody was raised against a synthetic peptide corresponding to amino acids at the C-terminus of human CARMA1.The immunogen is located within the last 50 amino acids of CARMA1. |
计算分子量 | 133kDa |
成分 | CARMA1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CARMA1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules.CARMA1,CARMA2,and CARMA3 share high degrees of sequence and functional homology,but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types.Both CARMA1 and CARMA3 associate with NEMO,the regulatory subunit of the I百K complex,thereby regulating activation of the NF-百B transcription factor.Also,gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS,indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems. |
Uniprot ID | Q9BXL7 |
基因名全称 | Caspase recruitment domain family,member 11 |
蛋白名全称 | Caspase recruitment domain family,member 11 |
推荐稀释比 | CARMA1 antibody can be used for detection of CARMA1 by Western blot at 0.5 to 2μg/mL.A band at approximately 125kDa can be detected.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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