产品货号：
Z29731
中文名称：
UNC93B1抗体
英文名称：
Anti-UNC93B1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UNC93B1 Antibody |
| 指标别名 | IIAE1,UNC93,UNC93B,Unc-93B1,Protein unc-93 homolog B1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | UNC93B1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Unc93b antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human Unc93b.The immunogen is located within amino acids 80 - 130 of Unc93b. |
| 计算分子量 | 67kDa |
| 成分 | Unc93b Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Unc93b Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The endoplasmic reticulum (ER) protein Unc93b,a human homolog of the C.elegans Unc93 gene,was initially identified by a forward genetic screen using N-ethyl-N-nitrosourea where a histidine-to-arginine substitution in Unc93b caused defects in Toll-like receptor (TLR) 3,7 and 9 signaling.Unlike Unc93a,another homolog of the C.elegans Unc93 gene whose function is unknown,Unc93b specifically interacts with TLR3,7 and 9;the histidine-to-arginine point mutation used to identify Unc93b abolishes this interaction.Mice carrying this point mutation are highly susceptible to infection with a number of viruses,indicating that Unc93b plays an important role in innate immunity. |
| Uniprot ID | Q9H1C4 |
| 基因名全称 | Unc-93 homolog B1 (C.elegans) |
| 蛋白名全称 | Unc-93 homolog B1 (C.elegans) |
| 推荐稀释比 | Unc93b antibody can be used for the detection of Unc93b by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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