产品货号：
Z29730
中文名称：
UPF2抗体
英文名称：
Anti-UPF2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UPF2 Antibody |
| 指标别名 | UPF2;KIAA1408;RENT2;Regulator of nonsense transcripts 2;Nonsense mRNA reducing factor 2;Up-frameshift suppressor 2 homolog;hUpf2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | UPF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human hUPF2/RENT2/UPF2 recombinant protein (Position:K200-H651). |
| 实际分子量 | 170KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD).When translation ends upstream from the last exon-exon junction,this triggers NMD to degrade mRNAs containing premature stop codons.This protein is located in the perinuclear area.It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p.Two splice variants have been found for this gene;both variants encode the same protein. |
| Uniprot ID | Q9HAU5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | UPF2 regulator of nonsense mediated mRNA decay |
| 蛋白名全称 | Regulator of nonsense transcripts UPF2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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