产品货号：
Z29694
中文名称：
UCMA抗体
英文名称：
Anti-UCMA Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UCMA Antibody |
| 指标别名 | GRP,C10orf49,Unique cartilage matrix-associated protein,Gla-rich protein,Ucma-C |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | UCMA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | UCMA antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human UCMA.The immunogen is located within the last 50 amino acids of UCMA. |
| 计算分子量 | 17kDa |
| 成分 | UCMA Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | UCMA Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | UCMA is a secreted cartilage-specific protein that was discovered in a screen for differentially expressed genes in retinoic acid-treated mouse chondrocytes.It was also identified in a human chondrocyte EST screen for candidate genes of skeletal dysplasias.UCMA expression is thought to parallel that of collagen II with its expression decreasing with maturation chrondrocytes mature.UCMA is processed by a furin-like protease into two fragments,an amino-terminal fragment and a carboxy-terminal fragment (UCMA-C).Application of recombinant UCMA-C to primary osteoblasts,mesenchymal stem cells,and MC3T3-E1 pre-osteoblasts interferes with their osteogenic differentiation,but does not affect expression of chondrocyte-specific genes or chondrocyte proliferation,suggesting that UCMA may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells.At least two isoforms of UCMA are known to exist. |
| Uniprot ID | Q8WVF2 |
| 基因名全称 | Upper zone of growth plate and cartilage matrix associated |
| 蛋白名全称 | Upper zone of growth plate and cartilage matrix associated |
| 推荐稀释比 | UCMA antibody can be used for detection of UCMA by Western blot at 2.5 ～ 5μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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