产品货号:
Z29665
中文名称:
UTRN抗体
英文名称:
Anti-UTRN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-UTRN Antibody |
指标别名 | UTRN;DMDL;DRP1;Utrophin;Dystrophin-related protein 1;DRP-1 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,ICC/IF,ELISA |
基因名称 | UTRN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Utrophin/UTRN recombinant protein (Position:L1211-K2294). |
实际分子量 | 394KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Utrophin is a protein that in humans is encoded by the UTRN gene.This gene shares both structural and functional similarities with the dystrophin gene.It contains an actin-binding N-terminus,a triple coiled-coil repeat central region,and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components.The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions,where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering.Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore,may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene.Alternative splicing of the utrophin gene has been described;however,the full-length nature of these variants has not yet been determined. |
Uniprot ID | P46939 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | utrophin |
蛋白名全称 | Utrophin |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 ELISA 1:100~1000 |
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