产品货号：
Z29502
中文名称：
UBA1抗体
英文名称：
Anti-UBA1 Antibody
产品规格：
500μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UBA1 Antibody |
| 指标别名 | A1S9;A1S9T;A1ST;AMCX1;GXP1;Protein A1S9;SMAX2;UBA1;UBA1A;UBE1;UBE1X;Ubiquitin activating enzyme E1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,WB |
| 基因名称 | UBA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-Ubiquitin Activating Enzyme E1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to full length Human Ubiquitin Activating Enzyme E1. |
| 计算分子量 | 118kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This antibody is directed against human Ubiquitin Activating Enzyme E1 protein.The product was protein A purified from monospecific antiserum followed by further purification to remove the GST tag.A BLAST analysis was used to suggest that this antibody would react with Ubiquitin Activating Enzyme E1 protein from human (100%) rabbit (96%),mouse (95%),rat (95%) and dog (93%) based on a high degree of sequence homology.Cross-reactivity against this protein from other sources has not been determined. |
| 浓度 | 1.2mg/mL by UV absorbance at 280nm |
| 产品形态 | Lyophilized |
| 保存条件 | Store vial at 4℃ prior to restoration.For extended storage aliquot contents and freeze at -20℃ or below.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.?Expiration date is one (1) year from date of opening. |
| 背景资料 | Ubiquitin Activating Enzyme (E1),also known as A1S9 and UBE1,is responsible for the first step in ubiquitin-protein isopeptide bond formation.E1 catalyzes the activation of the C-terminal carboxyl group of ubiquitin by forming a high-energy thioester bond in an ATP-dependent manner.UBE1 is monomeric and contains two active sites within the E1 molecule,allowing it to bind two ubiquitin moieties at a time,with a new ubiquitin forming an adenylate intermediate as the previous one is transferred to the thiol site.Alternative splicing results in 2 transcript variants encoding the same protein,but with different 5' UTR.Isoform 1 has a different 5' noncoding exon compared to isoform 2.Both variants encode the same protein. |
| Uniprot ID | P22314 |
| 基因名全称 | Ubiquitin-like modifier-activating enzyme 1 |
| 推荐稀释比 | ELISA:1:2,000 - 1:10,000 IHC:2mg/mL - 20μg/mL WB:1:1,000 - 1:5,000 |
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