产品货号：
Z29477
中文名称：
TYW1抗体
英文名称：
Anti-TYW1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TYW1 Antibody |
| 指标别名 | TYW1A,RSAFD1,YPL207W,S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase,Radical S-adenosyl methionine and flavodoxin domain-containing protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | TYW1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TYW1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TYW1.The immunogen is located within amino acids 520 - 570 of TYW1. |
| 计算分子量 | 84kDa |
| 成分 | TYW1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TYW1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | TYW1 antibody can be stored at 4℃,stable for one year.As with all antibodies care should be taken to avoid repeated freeze thaw cycles.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | TYW1,also known as TYW1A,RSAFD1 or YPL207W,is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process,thereby ensuring correct translation.TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7.Defects in some of the genes on chromosome 7 have been linked to Osteogenesis imperfecta,Williams-Beuren syndrome,Lissencephaly,Citrullinemia and Shwachman-Diamond syndrome,suggesting that TYW1 may play a role in these conditions |
| Uniprot ID | Q9NV66 |
| 基因名全称 | TRNA-yW synthesizing protein 1 homolog (S.cerevisiae) |
| 蛋白名全称 | TRNA-yW synthesizing protein 1 homolog (S.cerevisiae) |
| 推荐稀释比 | TYW1 antibody can be used for detection of TYW1 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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