产品货号:
Z29306
中文名称:
VDR抗体
英文名称:
Anti-VDR Antibody (Center)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-VDR Antibody (Center) |
指标别名 | VDR;NR1I1;Vitamin D3 receptor;VDR;1;25-dihydroxyvitamin D3 receptor;Nuclear receptor subfamily 1 group I member 1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,FCM |
基因名称 | VDR |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This VDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-299 amino acids from the Central region of human VDR. |
计算分子量 | 48kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | This gene encodes the nuclear hormone receptor for vitamin D3.This receptor also functions as a receptor for the secondary bile acid lithocholic acid.The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors.Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways,such as those involved in the immune response and cancer.Mutations in this gene are associated with type II vitamin D-resistant rickets.A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream.Alternative splicing results in multiple transcript variants encoding the same protein. |
Uniprot ID | P11473 |
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