产品货号：
Z29285
中文名称：
VDAC1/2抗体
英文名称：
Anti-VDAC1/2 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-VDAC1/2 antibody |
| 指标别名 | hVDAC1;Plasmalemmal porin;Porin;PORIN 31 HL;Porin 31HL;Porin 31HM;VDAC;VDAC 1;VDAC1;VDAC2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,IP,Direct ELISA |
| 基因名称 | VDAC1/VDAC2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human VDAC1/2 recombinant protein (Position:A2-E280). |
| 实际分子量 | 31KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane is a small,abundant outer membrane pore-forming protein found in the outer membranes of all eukaryotic mitochondria.The VDAC protein is thought to form the major pathway for movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol kinase.At low transmembrane voltage,VDAC is open for anions such as phosphate,chloride,and adenine nucleotides.At higher transmembrane voltage,VDAC functions as a selective channel for cations and uncharged molecules.These features make VDAC likely to play a role in mitochondrial energy metabolism.Huizing et al.studied by Northern and Western blot analyses the human tissue distribution of mitochondrial transmembrane metabolite carriers.They found that VDAC1 mRNA has a ubiquitous distribution,with most pronounced expression in heart,liver,and skeletal muscle,whereas the VDAC2 isoform appears to be expressed only in the heart. |
| Uniprot ID | P21796/P45880 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | voltage-dependent anion channel 1 |
| 蛋白名全称 | Voltage-dependent anion-selective channel protein 1(VDAC-1/hVDAC1) |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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