产品货号：
Z29243
中文名称：
Uromodulin/UMOD抗体
英文名称：
Anti-Uromodulin/UMOD Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Uromodulin/UMOD Antibody |
| 指标别名 | ADMCKD2;FJHN;HNFJ;MCKD2;THGP;THP;UMOD;uromodulin |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | UMOD |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human UMOD recombinant protein (Position:E43-S618). |
| 实际分子量 | 110KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Uromodulin (UMOD),also known as Tamm–Horsfall protein (THP),is a glycoprotein that in humans is encoded by the UMOD gene.The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions.Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle.This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids.Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria.Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2),glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI),and familial juvenile hyperuricemic nephropathy (FJHN).Alternative splicing of this gene results in multiple transcript variants. |
| Uniprot ID | P07911 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | uromodulin |
| 蛋白名全称 | Uromodulin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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