产品货号：
Z29222
中文名称：
TWIST1/2抗体
英文名称：
Anti-TWIST1/2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TWIST1/2 Antibody |
| 指标别名 | TWIST1;BHLHA38;TWIST;bHLHa38;H-twist;TWIST2;BHLHA39;DERMO1;Twist-related protein 2;bHLHa39;Dermo-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | TWIST1/TWIST2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human TWIST1/2 (KIIPTLPSDKLSKIQTLKLAARY). |
| 实际分子量 | 30KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Twist-related protein 1 (TWIST1) also known as class A basic helix–loop–helix protein 38 (bHLHa38) is a basic helix-loop-helix transcription factor that in humans is encoded by the TWIST1 gene.This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development.The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development.This protein may also regulate neural tube closure,limb development and brown fat metabolism.This gene is hypermethylated and overexpressed in multiple human cancers,and the encoded protein promotes tumor cell invasion and metastasis,as well as metastatic recurrence.Mutations in this gene cause Saethre-Chotzen syndrome in human patients,which is characterized by craniosynostosis,ptosis and hypertelorism. |
| Uniprot ID | Q15672/Q8WVJ9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | twist family bHLH transcription factor 1/2 |
| 蛋白名全称 | Twist-related protein 1/2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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