产品货号：
Z29212
中文名称：
TTC39B抗体
英文名称：
Anti-TTC39B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TTC39B Antibody |
| 指标别名 | TTC39B;C9orf52;Tetratricopeptide repeat protein 39B;TPR repeat protein 39B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM(Intracellular),ELISA |
| 基因名称 | TTC39B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human TTC39B recombinant protein (Position:K129-D682). |
| 实际分子量 | 70KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tetratricopeptide repeat protein 39B is a protein that in humans is encoded by the TTC39B gene.TTC39B protein contains two TPR repeats (aa 39 3-426 and 626 -659).TCC39B protein is the product of a high density lipoprotein (HDL) gene that promotes the ubiquitination and degradation of liver X receptor (LXR).TTC39B null or deficient mice challenged with high fat/cholesterol/bile salt diet exhibit increased LX R protein and target gene expression.TTC39B deficiency is reported to stabilize LXR by reducing its polyubiquitination and proteasomal degradation.Hence it reduces the incidence of atherosclerosis and steatohepatitis.TTC39B deficiency mice display higher levels of HDL and Apoplipoprotein A-1 and lower levels of hepatic triglyceride synthesis.However it does not affect glucose tolerance or hepatic gluconeogenesis. |
| Uniprot ID | Q5VTQ0 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | tetratricopeptide repeat domain 39B |
| 蛋白名全称 | Tetratricopeptide repeat protein 39B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Flow Cytometry(Intracellular) 1～3μg/1×106 cells ELISA 1:100～1000 |
| Gene ID | 158219 |
相关搜索：TTC39B抗体，TTC39B多抗，Anti-TTC39B Antibody