产品货号：
Z29204
中文名称：
TTBK2抗体
英文名称：
Anti-TTBK2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TTBK2 Antibody |
| 指标别名 | KIAA0847;SCA11;tau tubulin kinase 2;TTBK;TTBK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC |
| 基因名称 | TTBK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TTBK2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human TTBK2.The immunogen is located within the last 50 amino acids of TTBK2. |
| 计算分子量 | 137kDa |
| 成分 | TTBK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TTBK2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins.Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11),a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib,and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib,suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance. |
| Uniprot ID | Q6IQ55 |
| 基因名全称 | Tau tubulin kinase 2 |
| 蛋白名全称 | Tau tubulin kinase 2 |
| 推荐稀释比 | TTBK2 antibody can be used for detection of TTBK2 by immunohistochemistry at 5μg/mL.Antibody validated:Immunohistochemistry in human samples.All other applications and species not yet tested. |
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