产品货号：
Z29154
中文名称：
TRAC抗体
英文名称：
Anti-TRAC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TRAC Antibody |
| 指标别名 | T cell receptor alpha constant;IMD7;TCRA;TRA;TRCA;TRAC |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM(Intracellular),Direct ELISA |
| 基因名称 | TRAC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human TCR alpha recombinant protein (Position:P1-L116). |
| 实际分子量 | 45KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC).Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain.In a single cell,the T cell receptor loci are rearranged and expressed in the order delta,gamma,beta,and alpha.If both delta and gamma rearrangements produce functional chains,the cell expresses delta and gamma.If not,the cell proceeds to rearrange the beta and alpha loci.This region represents the germline organization of the T cell receptor alpha and delta loci.Both the alpha and delta loci include V (variable),J (joining),and C (constant) segments and the delta locus also includes diversity (D) segments.The delta locus is situated within the alpha locus,between the alpha V and J segments.During T cell development,the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment;a V segment is then joined to the D-J gene.The alpha chain is synthesized by recombination joining a single V segment with a J segment.For both chains,the C segment is later joined by splicing at the RNA level.Recombination of many different V segments with several J segments provides a wide range of antigen recognition.Additional diversity is attained by junctional diversity,resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase.Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols.Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. |
| Uniprot ID | P01848 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow Cytometry(FCM) 1～3μg/1×106 cells Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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