产品货号：
Z29107
中文名称：
transgelin/SM22/TAGLN抗体
英文名称：
Anti-transgelin/SM22/TAGLN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-transgelin/SM22/TAGLN Antibody |
| 指标别名 | SM22;SM22 alpha;SM22a;SM22alpha;TAGLN;TAGLN1;transgelin;transgelin/SM22 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ICC/IF,FCM,ELISA |
| 基因名称 | TAGLN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human TAGLN/Transgelin recombinant protein (Position:Q15-E170). |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Transgelin,also known as SM22 alpha,is a protein that in humans is encoded by the TAGLN gene.This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family.It is ubiquitously expressed in vascular and visceral smooth muscle,and is an early marker of smooth muscle differentiation.The encoded protein is thought to be involved in calcium-independent smooth muscle contraction.It acts as a tumor suppressor,and the loss of its expression is an early event in cell transformation and the development of some tumors,coinciding with cellular plasticity.The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain.Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. |
| Uniprot ID | Q01995 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | transgelin |
| 蛋白名全称 | Transgelin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Immunofluorescence (IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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