产品货号：
Z29092
中文名称：
UBQLN4抗体
英文名称：
Anti-UBQLN4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UBQLN4 Antibody |
| 指标别名 | Ubiquilin-4;Ataxin-1 interacting ubiquitin-like protein;A1Up;Ataxin-1 ubiquitin-like-interacting protein A1U;Connexin43-interacting protein of 75kDa;CIP75;UBQLN4;C1orf6;CIP75;UBIN |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | UBQLN4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CIP75 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CIP75.The immunogen is located within the first 50 amino acids of CIP75. |
| 计算分子量 | 64kDa |
| 成分 | CIP75 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CIP75 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins.The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation.One such protein is CIP75,also known as ubiquilin-4,interacts with a number of proteins such as Ataxin-1 and Connexin-43,resulting in an increased rate of turnover of these proteins.Overexpression CIP75 led to a significant reduction of Connexin-43 half-life,with the opposite being observed in siRNA knockdown experiments.CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteosome complex and a C-terminal UBA domain which appears to mediate its interaction with Connexin-75.At least three isoforms of CIP75 are known to exist. |
| Uniprot ID | Q9NRR5 |
| 基因名全称 | Ubiquilin 4 |
| 蛋白名全称 | Ubiquilin 4 |
| 推荐稀释比 | CIP75 antibody can be used for detection of CIP75 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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