产品货号：
Z28928
中文名称：
UBE2V1抗体
英文名称：
Anti-UBE2V1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-UBE2V1 Antibody |
| 指标别名 | CIR1;UEV1;CROC1;UBE2V;UEV-1;UEV1A;CROC-1;P/OKcl.19;Ubiquitin-conjugating enzyme E2 variant 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | UBE2V1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | UEV1A antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human UEV1A.The immunogen is located within the last 50 amino acids of UEV1A. |
| 计算分子量 | 16kDa |
| 成分 | UEV1A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | UEV1A Antibody is Ion exchange chromatography purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Ubiquitin-conjugating enzyme E2 (UEV1) was initially discovered as a protein similar in sequence and structure to the E2 ubiquitin-conjugating enzymes but lacking their enzymatic activity.There are at least two variants and multiple isoforms of UEV1.In particular,UEV1A (Ubiquitin-conjugating enzyme E2 variant 1 isoform A) has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway.Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6),ultimately activating various kinases and transcription factors.UEV1A is part of a dimeric ubiquitin-conjugating enzyme complex also containing Ubc13 (ubiquitin-conjugating enzyme 13) that together with TRAF6 activates TAK1,a member of the mitogen-activated protein kinase kinase kinase family.The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6,and this ubiquitination is essential for TAK1 activation. |
| Uniprot ID | Q13404 |
| 基因名全称 | Ubiquitin-conjugating enzyme E2 variant 1 |
| 蛋白名全称 | Ubiquitin-conjugating enzyme E2 variant 1 |
| 推荐稀释比 | UEV1A antibody can be used for detection of UEV1A by Western blot at 1 to 4μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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