产品货号:
Z28902
中文名称:
Ubiquitin/UBC抗体
英文名称:
Anti-Ubiquitin/UBC Antibody (N-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Ubiquitin/UBC Antibody (N-term) |
指标别名 | Polyubiquitin-C,Ubiquitin,UBC |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | IHC-Leica,WB |
基因名称 | UBC |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This Ubiquitin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human Ubiquitin. |
计算分子量 | 77kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | This gene encodes ubiquitin,one of the most conserved proteins known.Ubiquitin is required for ATP-dependent,nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover.Ubiquitin is covalently bound to proteins to be degraded,and presumably labels these proteins for degradation.Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation,suggesting that ubiquitin is also involved in regulation of gene expression.This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence.Consequently,the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat.Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. |
Uniprot ID | P0CG48 |
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