产品货号:
Z28897
中文名称:
TRMT12抗体
英文名称:
Anti-TRMT12 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRMT12 Antibody |
指标别名 | TYW2;TRM12;TYW2;tRNA wybutosine-synthesizing protein 2 homolog;Alpha-amino-alpha-carboxypropyl transferase TYW2;tRNA-yW-synthesizing protein 2 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,ICC |
基因名称 | TRMT12 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TYW2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TYW2.The immunogen is located within the first 50 amino acids of TYW2. |
计算分子量 | 50kDa |
成分 | TYW2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TYW2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | TYW2 antibody can be stored at 4℃,stable for one year.As with all antibodies care should be taken to avoid repeated freeze thaw cycles.Antibodies should not be exposed to prolonged high temperatures. |
背景资料 | TYW2,also known as TRM12,is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway.Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome.TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process,thereby ensuring correct translation.TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed,and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26,suggesting that TYW2 may play a role in breast cancer. |
Uniprot ID | Q53H54 |
基因名全称 | TRNA methyltransferase 12 homolog |
蛋白名全称 | TRNA methyltransferase 12 homolog |
推荐稀释比 | TYW2 antibody can be used for detection of TYW2 by Western blot at 0.5μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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