产品货号:
Z28822
中文名称:
TRIM21抗体
英文名称:
Anti-TRIM21 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRIM21 Antibody |
指标别名 | 52kDa Ro protein;RING finger protein 81;RNF81;Ro(SS A);RO52;SS A;SSA;SSA1;TRIM21;tripartite motif containing 21 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | TRIM21 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Anti-TRIM21 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TRIM21.The immunogen is located within amino acids 290-340 of TRIM21. |
计算分子量 | 54kDa |
成分 | TRIM21 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRIM21 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | TRIM21,a member of the tripartite motif (TRIM) family,is a part of the RoSSA ribonucleoprotein,which includes a single polypeptide and one of four small RNA molecules.The RoSSA particle localizes to both the cytoplasm and the nucleus (1).RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus (2).TRIM21 also acts as a cytosolic antibody receptor;detection of intracellular antibodies activate immune signaling by stimulating the transcription factor pathways of NF-kappaB,AP-1,IRF3,IRF5,and IRF7,resulting in the production of proinflammatory cytokines and the induction of an antiviral state (3). |
Uniprot ID | P19474 |
基因名全称 | Tripartite motif containing 21 |
蛋白名全称 | Tripartite motif containing 21 |
推荐稀释比 | WB:0.5~2μg/mL;IHC:5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples;Immunofluorescence in human samples.All other applications and species not yet tested. |
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