产品货号：
Z28748
中文名称：
TREM1抗体
英文名称：
Anti-TREM1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TREM1 Antibody |
| 指标别名 | CD354;TREM 1;TREM1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,ELISA(Cap) |
| 基因名称 | Trem1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse TREM1 recombinant protein (Position:A21-S202). |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Trem1,Triggering receptor expressed on myeloid cells-1,is encoded by Trem1 gene.The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes,dendritic cells,or other cell types.Trem1 is a 30-kD glycoprotein that is reduced to 26kD by deglycosylation,in agreement with the predicted molecular mass.The Trem1 gene which contains 4 exons maps to chromosome 6p21.1,within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6.The expression of Trem1 is upregulated by stimulation with lipopolysaccharide (LPS),gram-negative bacteria,and fungi.Cross-linking of Trem1 on neutrophils induces interleukin-8 (IL8) and myeloperoxidase secretion,while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1 (MCP1,or SCYA2) and tumor necrosis factor (TNF);MCP1 and TNF secretion could be further upregulated by LPS-mediated priming.Trem1 engagement also induces upregulation of adhesion molecules (e.g.,ITGB1) and costimulatory molecules (e.g.,CD40).Trem1 is associated with DAP12 (TYROBP),a molecule frequently associated with activating receptors. |
| Uniprot ID | Q9JKE2 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 ELISA(Cap) 1:50～1:200 |
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