产品货号:
Z28663
中文名称:
TRAF6抗体
英文名称:
Anti-TRAF6 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRAF6 Antibody |
指标别名 | TNF receptor associated factor 6;MGC:3310;RNF85;TRAF6 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | TRAF6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRAF6.The immunogen is located within the last 50 amino acids of TRAF6. |
计算分子量 | 60kDa |
成分 | TRAF6 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRAF6 Antibody is Ion exchange chromatography purified. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells.Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-百B.TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families.TRAF6 is important in cytokine production,dendritic cell (DC) maturation,and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands.It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) or by other TLR adaptor molecules such as TRIF.Also,it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK. |
Uniprot ID | Q9Y4K3 |
基因名全称 | TNF receptor-associated factor 6 |
蛋白名全称 | TNF receptor-associated factor 6 |
推荐稀释比 | TRAF6 antibody can be used for detection of TRAF6 by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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