产品货号：
Z28662
中文名称：
TRAF6抗体
英文名称：
Anti-TRAF6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TRAF6 Antibody |
| 指标别名 | TNF receptor associated factor 6;MGC:3310;RNF85;Traf6 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | Traf6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse TRAF6 recombinant protein (Position:Q14-D512). |
| 实际分子量 | 60KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TNF receptor-associated factor 6,also called E3 ubiquitin-protein ligase TRAF6 or RNF85,is a TRAF human protein.The protein encoded by this gene is a member of the TNF receptor associated factor(TRAF) protein family.TRAF proteins are associated with,and mediate signal transduction from,members of the TNF receptor superfamily.This gene is mapped to 11p12.This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family.Signals from receptors such as CD40,TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein.This protein also interacts with various protein kinases including IRAK1/IRAK,SRC and PKCzeta,which provides a link between distinct signaling pathways.This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase(IKK) in response to proinflammatory cytokines.The interaction of this protein with UBE2N/UBC13,and UBE2V1/UEV1A,which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains,has been found to be required for IKK activation by this protein. |
| Uniprot ID | P70196 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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