产品货号：
Z28617
中文名称：
TNNI2抗体
英文名称：
Anti-TNNI2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TNNI2 Antibody |
| 指标别名 | AMCD2B;DA2B;FSSV;fsTnI;TNNI2;Troponin I fast skeletal muscle;Troponin I;fast-twitch isoform |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ELISA |
| 基因名称 | TNNI2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Troponin I fast skeletal muscle/TNNI2 recombinant protein (Position:D3-S182). |
| 实际分子量 | 21KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Troponin I,fast skeletal muscle is a protein that in humans is encoded by the TNNI2 gene.It is mapped to 11p15.5.This gene encodes a fast-twitch skeletal muscle protein,a member of the troponin I gene family,and a component of the troponin complex including troponin T,troponin C and troponin I subunits.The troponin complex,along with tropomyosin,is responsible for the calcium-dependent regulation of striated muscle contraction.Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function.In addition to muscle tissues,this protein is found in corneal epithelium,cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis,and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha.This protein also suppresses tumor growth in human ovarian carcinoma.Mutations in this gene cause myopathy and distal arthrogryposis type 2B.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | P48788 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot 1:500～2000 Immunohistochemistry in paraffin section 1:50～400 Immunofluorescence (IF) 1:50～400 Direct ELISA： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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