产品货号:
Z28616
中文名称:
TNNI1抗体
英文名称:
Anti-TNNI1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TNNI1 Antibody |
指标别名 | SSTNI;TNN1;TNNI1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | TNNI1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence of human TNNI1 (REAEKVRYLAERIPTLQTR). |
实际分子量 | 22KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Troponin I,slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene.Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles.Troponin I (TnI),along with troponin T (TnT) and troponin C (TnC),is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle.TnI is the inhibitory subunit;blocking actin-myosin interactions and thereby mediating striated muscle relaxation.The TnI subfamily contains three genes:TnI-skeletal-fast-twitch,TnI-skeletal-slow-twitch,and TnI-cardiac.The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers,respectively,while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue.This gene encodes the Troponin-I-skeletal-slow-twitch protein.This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults.The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. |
Uniprot ID | P19237 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
基因名全称 | troponin I1,slow skeletal type |
蛋白名全称 | Troponin I,slow skeletal muscle |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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