产品货号：
Z28586
中文名称：
TET1抗体
英文名称：
Anti-TET1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TET1 Antibody |
| 指标别名 | tet methylcytosine dioxygenase 1;CXXC6;LCX;bA119F7.1;TET1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | TET1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-TET1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET1.The immunogen is located within amino acids 2030 - 2080 of TET1. |
| 计算分子量 | 235kDa |
| 成分 | TET1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TET1 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TET1,a member of the ten-eleven-translocation (TET) family of genes,was initially discovered as a fusion partner of MLL in acute myeloid leukemias containing the t(10;11)(q22;q23) (1).It is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine (2).TET1 expression is regulated during inflammation in both THP-1 and primary dendritic cells,and is a negative transcriptional regulator of IL-1beta following and inflammatory stimulus (3).Recent evidence has shown that TET1 is part of a signaling pathway that regulates breast cancer growth and metastasis (4). |
| Uniprot ID | Q8NFU7 |
| 基因名全称 | Tet methylcytosine dioxygenase 1 |
| 蛋白名全称 | Tet methylcytosine dioxygenase 1 |
| 推荐稀释比 | WB:1μg/mL;IHC:1μg/mL;IF:20μg/mL.Antibody validated:Western Blot and Immunohistochemistry in human,mouse and rat samples;Immunocytochemistry in human samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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