产品货号：
Z28564
中文名称：
TNFAIP3抗体
英文名称：
Anti-TNFAIP3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TNFAIP3 Antibody |
| 指标别名 | A20;OTUD7C;TNF alpha induced protein 3;TNFA1P2;TNFAIP3;Zinc finger protein A20 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | TNFAIP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TNFAIP3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TNFAIP3.The immunogen is located within the last 50 amino acids of TNFAIP3. |
| 计算分子量 | 88kDa |
| 成分 | TNFAIP3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TNFAIP3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TNFAIP3,also known as A20,is located in chromosome band 6q23,a region that is often deleted in B cell lymphomas.Recently,it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas.TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-汐，inhibiting NF-百B-dependent gene expression,and protecting cells from TNF-汐-cytotoxicity.Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells,suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses,thereby protecting the host against harmful over-responses to pathogens.At least two isoforms of TNFAIP3 are known to exist. |
| Uniprot ID | Q60769 |
| 基因名全称 | Tumor necrosis factor,alpha-induced protein 3 |
| 蛋白名全称 | Tumor necrosis factor,alpha-induced protein 3 |
| 推荐稀释比 | TNFAIP3 antibody can be used for detection of TNFAIP3 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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