产品货号:
Z28539
中文名称:
TRIM30抗体
英文名称:
Anti-TRIM30 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRIM30 Antibody |
指标别名 | Rpt1;Rpt-1;Trim30;Rpt1;Tripartite motif-containing protein 30A;Down regulatory protein of interleukin-2 receptor |
克隆性 | Polyclonal |
检验物种 | mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | TRIM30 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TRIM30 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the mouse TRIM30.The immunogen is located within amino acids 250 - 300 of TRIM30. |
计算分子量 | 57kDa |
成分 | TRIM30 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRIM30 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation,differentiation,development,oncogenesis,apoptosis and antiviral responses.The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins,also known as RBCC proteins as they contain an RBCC motif,which comprises a RING domain,one or two B-boxes and a predicted coiled-coil region.Studies have shown that some TRIM family members are critical to innate immunity;TRIM5,TRIM19 and TRIM25,for example,have been shown to restrict viral infection.A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway,by targeting TAB2 and TAB3,and contributes to the inhibition of TLR-mediated NF-百B activation.The importance of TRIM30 in the attenuation or termination of NF-百B activation suggests that targeting of TAB2 and TAB3 by TRIM30汐may be a mechanism for modulating many types of immune responses. |
Uniprot ID | P15533 |
基因名全称 | Tripartite motif-containing 30 |
蛋白名全称 | Tripartite motif-containing 30 |
推荐稀释比 | TRIM30 antibody can be used for detection of TRIM30 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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