产品货号:
Z28522
中文名称:
TRIM5抗体
英文名称:
Anti-TRIM5 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TRIM5 Antibody |
指标别名 | tripartite motif containing 5;RNF88alpha;TRIM5 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | TRIM5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TRIM5 gamma antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of human TRIM5 gamma.The immunogen is located within the last 50 amino acids of TRIM5 gamma. |
计算分子量 | 56kDa |
成分 | TRIM5 gamma Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TRIM5 gamma Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain,a B-box type 1,and a B-box type 2,followed by a coiled-coil region.TRIM5 has five alternately spliced isoforms,the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain.While a function has not yet been assigned to TRIM5gamma,it is known that expression of TRIM5汐variants from humans,rhesus monkeys,and African green monkeys enable resistance to infection by various retroviruses including HIV-1,albeit at differing efficiencies.Furthermore,the TRIM5汛isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner. |
Uniprot ID | Q9C035 |
基因名全称 | Tripartite motif-containing 5 |
蛋白名全称 | Tripartite motif-containing 5 |
推荐稀释比 | TRIM5 gamma antibody can be used for detection of TRIM5 gamma by Western blot at 2μg/mL.A band at approximately 35kDa can be detected.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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