产品货号：
Z28521
中文名称：
TLR2抗体
英文名称：
Anti-TLR2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TLR2 Antibody |
| 指标别名 | CD282;TIL4;TLR2;toll like receptor 2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | TLR2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human TLR2 |
| 实际分子量 | 90KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Members of the Toll-like receptor (TLR) family,named for the closely related Toll receptor in Drosophila,play a pivotal role in innate immune responses (1-3).TLRs recognize conserved motifs found in various pathogens and mediate defense responses.Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes.The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain.Upon activation,TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor),MAL/TIRAP (MyD88-adaptor-like/TIR-associated protein),TRIF (Toll-receptor-associated activator of interferon),and TRAM (Toll-receptor-associated molecule).This association leads to the recruitment and activation of IRAK1 and IRAK4,which form a complex with TRAF6 to activate TAK1 and IKK.Activation of IKK leads to the degradation of IκB that normally maintains NF-κB inactivity by sequestering it in the cytoplasm. |
| Uniprot ID | O60603 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：TLR2抗体，TLR2多抗，Anti-TLR2 Antibody