产品货号：
Z28473
中文名称：
TNFSF18抗体
英文名称：
Anti-TNFSF18 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TNFSF18 Antibody |
| 指标别名 | AITRL;GITRL;hGITRL;TL6;TNFSF18 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | TNFSF18 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | GITRL antibody was raised against purified recombinant human GITR ligand. |
| 计算分子量 | 23kDa |
| 成分 | GITRL Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | GITRL Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation,differentiation,and survival through regulating the activation of the transcription factor NF-百B and various mitogen-activated protein kinases.The glucocorticoid-induced tumor necrosis factor receptor (GITR) is an emerging member of this family that is expressed on CD4+ CD25+ regulatory T cells and appears to have crucial immune regulation functions.Its ligand GITRL is expressed in endothelial and antigen-presenting cells and can activate NF-百B,induce both pro- and anti-apoptotic effects,inhibit the suppressive activity of regulatory T cells,and co-stimulate responder T cells through GITR.Dominant negative forms of NIK and TRAF2 expressed in transfected 293 cells substantially inhibited NF-百B activation,suggesting that the GITRL-GITR pathway involves both NIK and TRAF2. |
| Uniprot ID | Q9UNG2 |
| 基因名全称 | Tumor necrosis factor (ligand) superfamily,member 18 |
| 蛋白名全称 | Tumor necrosis factor (ligand) superfamily,member 18 |
| 推荐稀释比 | GITRL antibody can be used for the detection of GITRL by Western blot at 1μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.Antibody validated:Immunocytochemistry in human samples.All other applications and species not yet tested. |
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