产品货号：
Z28451
中文名称：
TBC1D1抗体
英文名称：
Anti-TBC1D1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TBC1D1 Antibody |
| 指标别名 | KIAA1108;TBC;TBC1;TBC1 domain family member 1;TBC1D1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | TBC1D1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TBC1D1 antibody was raised against a 22 amino acid synthetic peptide from near the carboxy terminus of human TBC1D1.The immunogen is located within the last 50 amino acids of TBC1D1. |
| 计算分子量 | 133kDa |
| 成分 | TBC1D1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TBC1D1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain and presumed to have a role in regulating cell growth and differentiation.These proteins share significant homology with TRE2/USP6,yeast Bub2,and CDC16.TBC1D1 and TBC1D4 (AS160) have been demonstrated to be Rab GAPs (GTPase-activating proteins) that link upstream to Akt and phosphoinositide 3-kinase and downstream to Rabs involved in trafficking of GLUT4 vesicles.TBC1D1 regulates insulin-mediated GLUT4 translocation through its GAP activity,and is a likely Akt substrate.Mutations in the Tbc1d1 gene lead to some cases of severe human obesity. |
| Uniprot ID | Q86TI0 |
| 基因名全称 | TBC1 (tre-2/USP6,BUB2,cdc16) domain family,member 1 |
| 蛋白名全称 | TBC1 (tre-2/USP6,BUB2,cdc16) domain family,member 1 |
| 推荐稀释比 | TBC1D1 antibody can be used for detection of TBC1D1 by Western blot at 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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