产品货号:
Z28421
中文名称:
TDT/DNTT抗体
英文名称:
Anti-TDT/DNTT Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TDT/DNTT Antibody |
指标别名 | DNA nucleotidylexotransferase;DNTT;TDT;Terminal addition enzyme;Terminal transferase |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | DNTT |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human TdT recombinant protein (Position:K316-A509).Human TdT shares 81% amino acid (aa) sequence identity with mouse TdT. |
实际分子量 | 59KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Terminal Deoxynucleotidyl Transferase,also known as TDT and terminal transferase,is a unique DNA polymerase without template direction catalyzes the addition of deoxyribonucleotides onto the 3-prime-hydroxyl end of DNA primers.Its gene is mapped to the region 10q23-q24.And TDT cDNA contains an open reading frame of 1,530 basepairs corresponding to a protein containing 510 amino acids.TDT may be responsible for inserting nucleotides (N regions) at the V(H)-D and D-J(H) junctions of immunoglobulin genes.The enzyme is present in immature thymocytes,some bone marrow cells,transformed pre-B and pre-T cell lines,and leukemia cells.Additionally,TDT catalyses the addition of nucleotides to the 3' terminus of a DNA molecule.Unlike most DNA polymerases it does not require a template.The preferred substrate of this enzyme is a 3'-overhang,but it can also add nucleotides to blunt or recessed 3' ends.Cobalt is a necessary cofactor. |
Uniprot ID | P04053 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | DNA nucleotidylexotransferase |
蛋白名全称 | DNA nucleotidylexotransferase |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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