产品货号:
Z28216
中文名称:
TIMP2抗体
英文名称:
Anti-TIMP2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TIMP2 Antibody |
指标别名 | CSC 21K;Metalloproteinase inhibitor 2;TIMP 2;TIMP2;TIMP-2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | IHC,ELISA |
基因名称 | TIMP2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP2(205-220aa RGAAPPKQEFLDIEDP),identical to the related mouse and rat sequences. |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | TIMP metallopeptidase inhibitor 2,a tissue inhibitor of metalloproteinases,also known as TIMP2,is a human gene,thought to be a metastasis suppressor.This gene is a member of the TIMP gene family.The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases,a group of peptidases involved in degradation of the extracellular matrix.In addition to an inhibitory role against metalloproteinases,the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells.As a result,the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors,and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. |
Uniprot ID | P16035 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | TIMP metallopeptidase inhibitor 2 |
蛋白名全称 | Metalloproteinase inhibitor 2 |
推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50~400 ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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