产品货号：
Z28146
中文名称：
TBP抗体
英文名称：
Anti-TBP Antibody (Center)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TBP Antibody (Center) |
| 指标别名 | GTF2D;GTF2D1;SCA17;TATA binding factor;TATA box binding protein;TATA box factor;TATA sequence binding protein;TBP;TF2D;TFIID |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IF,FCM,IHC |
| 基因名称 | TBP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This TBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human TBP. |
| 计算分子量 | 38kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides.The protein that coordinates these activities is transcription factor IID (TFIID),which binds to the core promoter to position the polymerase properly,serves as the scaffold for assembly of the remainder of the transcription complex,and acts as a channel for regulatory signals.TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs.TAFs may participate in basal transcription,serve as coactivators,function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.A distinctive feature of TBP is a long string of glutamines in the N-terminal.This region of the protein modulates the DNA binding activity of the C terminus,and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription.Mutations that expand the number of CAG repeats encoding this polyglutamine tract,and thus increase the length of the polyglutamine string,are associated with spinocerebellar ataxia 17,a neurodegenerative disorder classified as a polyglutamine disease. |
| Uniprot ID | P20226 |
相关搜索：TBP抗体，TBP(Center)多抗，Anti-TBP Antibody (Center)