产品货号：
Z28065
中文名称：
TAF1抗体
英文名称：
Anti-TAF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TAF1 Antibody |
| 指标别名 | BA2R;CCG1;CCGS;Cell cycle gene 1 protein;DYT3;KAT4;N TAF1;NSCL2;OF;P250;TAF(II)250;TAF1;TAF1-Specific;TAF2A;TAFII 250;TAFII250;TBP associated factor 250kDa |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | TAF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human TAF1 recombinant protein (Position:H1375-D1636). |
| 实际分子量 | 250～300KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Transcription initiation factor TFIID subunit 1,also known as transcription initiation factor TFIID 250kDa subunit (TAFII-250) or TBP-associated factor 250kDa (p250),is a protein that in humans is encoded by the TAF1 gene.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides.The protein that coordinates these activities is the basal transcription factor TFIID,which binds to the core promoter to position the polymerase properly,serves as the scaffold for assembly of the remainder of the transcription complex,and acts as a channel for regulatory signals.TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs.TAFs may participate in basal transcription,serve as coactivators,function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.This gene encodes the largest subunit of TFIID.This subunit binds to core promoter sequences encompassing the transcription start site.It also binds to activators and other transcriptional regulators,and these interactions affect the rate of transcription initiation.This subunit contains two independent protein kinase domains at the N- and C-terminals,but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme.Mutations in this gene result in Dystonia 3,torsion,X-linked,a dystonia-parkinsonism disorder.Alternative splicing of this gene results in multiple transcript variants.This gene is part of a complex transcription unit (TAF1/DYT3),wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons. |
| Uniprot ID | P21675 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | TATA-box binding protein associated factor 1 |
| 蛋白名全称 | Transcription initiation factor TFIID subunit 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 |
相关搜索：TAF1抗体，TAF1多抗，Anti-TAF1 Antibody